- aut = "Fabrizio Thorel"
- Artículo:
Conversion of adult pancreatic ?-cells to ?-cells after extreme ?-cell loss
- Autor:
Fabrizio Thorel
- Resumen:
In the pancreas, insulin-producing ?-cells are long-lived and generally replicate seldom. They can do so, however, after increased metabolic demand or after injury. Here, a new transgenic model is developed in which ?-cells are nearly completely ablated in mice. If given insulin, these mice survive, and grow new ?-cells. Lineage-tracing shows that these new ?-cells come from ?-cells, revealing a previously disregarded degree of pancreatic cell plasticity
- Página:
1149
- Publicación:
Nature
- Volúmen:
464
- Número:
7292
- Periodo:
22 Abril 2010
- ISSN:
00280836
- SrcID:
00280836-2010-04-22.txt
- Documento número 307403
- Actualizado el martes, 23 de mayo de 2017 03:58:15 p. m.
- Creado el martes, 23 de mayo de 2017 03:58:15 p. m.
- Enlace directo
- Artículo:
Conversion of adult pancreatic ?-cells to ?-cells after extreme ?-cell loss
- Autor:
Fabrizio Thorel
- Resumen:
In the pancreas, insulin-producing ?-cells are long-lived and generally replicate seldom. They can do so, however, after increased metabolic demand or after injury. Here, a new transgenic model is developed in which ?-cells are nearly completely ablated in mice. If given insulin, these mice survive, and grow new ?-cells. Lineage-tracing shows that these new ?-cells come from ?-cells, revealing a previously disregarded degree of pancreatic cell plasticity
- Página:
1149
- Publicación:
Nature
- Volúmen:
464
- Número:
7292
- Periodo:
22 Abril 2010
- ISSN:
00280836
- SrcID:
00280836-2010-04-22.txt
- Documento número 539507
- Actualizado el martes, 10 de julio de 2018 10:13:50 a. m.
- Creado el martes, 10 de julio de 2018 10:13:50 a. m.
- Enlace directo
- Artículo:
Conversion of adult pancreatic ?-cells to ?-cells after extreme ?-cell loss
- Autor:
Fabrizio Thorel
- Resumen:
In the pancreas, insulin-producing ?-cells are long-lived and generally replicate seldom. They can do so, however, after increased metabolic demand or after injury. Here, a new transgenic model is developed in which ?-cells are nearly completely ablated in mice. If given insulin, these mice survive, and grow new ?-cells. Lineage-tracing shows that these new ?-cells come from ?-cells, revealing a previously disregarded degree of pancreatic cell plasticity
- Página:
1149
- Publicación:
Nature
- Volúmen:
464
- Número:
7292
- Periodo:
22 Abril 2010
- ISSN:
00280836
- SrcID:
00280836-2010-04-22.txt
- Documento número 1206272
- Actualizado el martes, 10 de julio de 2018 11:33:56 a. m.
- Creado el martes, 10 de julio de 2018 11:33:56 a. m.
- Enlace directo
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