Artículo:

HDAC2 negatively regulates memory formation and synaptic plasticity

Autor:

Ji-Song Guan

Stephen J. Haggarty

Emanuela Giacometti

Resumen:

Histone acetylation has been implicated in learning and memory. Neuron-specific overexpression of histone deacetylase 2 (HDAC2), but not HDAC1, is shown to decrease memory formation in a rodent model

Página:

55

Sección:

Article

Publicación:

Nature

Volúmen:

459

Número:

7243

Fecha:

7 Mayo 2009

ISSN:

00280836

SrcID:

00280836-2009-05-07.txt