Artículo:

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

Autor:

Roland Schmitz, Ryan M. Young, Michele Ceribelli, Sameer Jhavar, Wenming Xiao+ et al.

Resumen:

RNA sequencing of Burkitt lymphoma tumours allows identification of mutations affecting the transcription factor TCF3, its negative regulator ID3 and the cell cycle regulator CCND3; these pathways reveal new targets for potential therapeutic intervention.

Página:

116

Sección:

LETTERS

Publicación:

Nature

Volúmen:

490

Número:

7418

Periodo:

4 octubre 2012

ISSN:

00280836

SrcID:

00280836-2012-10-04.txt