Catálogo de revistas impresas de la biblioteca

Se encontraron 64 resultados.

Artículo:: Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive
Autor:: Julia C. Lemos, Matthew J. Wanat, Jeffrey S. Smith, Beverly A. S. Reyes, Nick G. Hollon+ et al.
Resumen:: The neuropeptide corticotropin-releasing factor (CRF) acts in the nucleus accumbens of mice to increase dopamine release through coactivation of CRF receptor 1 (CRFR1) and CRFR2, but exposure to severe stress results in loss of this regulation and a switch in the reaction to CRF from appetitive to aversive.
Página:: 402
Sección:: LETTERS
Publicación:: Nature
Volúmen:: 490
Número:: 7420
Periodo:: 18 octubre 2012
ISSN:: 00280836
SrcID:: 00280836-2012-10-18.txt

Artículo:: Androgenetic haploid embryonic stem cells produce live transgenic mice
Autor:: Wei Li, Ling Shuai, Haifeng Wan, Mingzhu Dong, Meng Wang+ et al.
Resumen:: Mouse androgenetic haploid embryonic stem cell lines can be established by transferring sperm into an enucleated oocyte; the cells maintain haploidy and stable growth over 30?passages, express pluripotent markers, are able to differentiate into all three germ layers, contribute to germlines of chimaeras when injected into blastocysts and can produce fertile progeny that carry genetic modifications to the next generation.
Página:: 407
Sección:: LETTERS
Publicación:: Nature
Volúmen:: 490
Número:: 7420
Periodo:: 18 octubre 2012
ISSN:: 00280836
SrcID:: 00280836-2012-10-18.txt

Artículo:: Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation
Autor:: Jennifer Landsberg, Judith Kohlmeyer, Marcel Renn, Tobias Bald, Meri Rogava+ et al.
Resumen:: A genetically engineered mouse model is used to determine the mechanism of acquired resistance to adoptive therapy with cytotoxic T cells specific for a melanocytic differentiation antigen; tumour necrosis factor (TNF)-? is identified as a crucial factor that causes reversible dedifferentiation of mouse and human melanoma cells.
Página:: 412
Sección:: LETTERS
Publicación:: Nature
Volúmen:: 490
Número:: 7420
Periodo:: 18 octubre 2012
ISSN:: 00280836
SrcID:: 00280836-2012-10-18.txt

Artículo:: Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
Autor:: Morgane Rolland, Paul T. Edlefsen, Brendan B. Larsen, Sodsai Tovanabutra, Eric Sanders-Buell+ et al.
Resumen:: Genetic analysis of breakthrough infections in people vaccinated against HIV-1 show that vaccine efficacy increased by up to 80% against viruses carrying two mutations in Env V2, but also raises the possibility of population-level adaptation to the vaccine.
Página:: 417
Sección:: LETTERS
Publicación:: Nature
Volúmen:: 490
Número:: 7420
Periodo:: 18 octubre 2012
ISSN:: 00280836
SrcID:: 00280836-2012-10-18.txt

Artículo:: A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
Autor:: Vladimir Litvak, Alexander V. Ratushny, Aaron E. Lampano, Frank Schmitz, Albert C. Huang+ et al.
Resumen:: FOXO3 is a negative regulator of IRF7, a master regulator of the antiviral response.
Página:: 421
Sección:: LETTERS
Publicación:: Nature
Volúmen:: 490
Número:: 7420
Periodo:: 18 octubre 2012
ISSN:: 00280836
SrcID:: 00280836-2012-10-18.txt

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