The harlequin frogs of tropical America are at the sharp end of climate change. About two-thirds of their species have died out, and altered patterns of infection because of changes in temperature seem to be the cause.

The harlequin frogs of tropical America are at the sharp end of climate change. About two-thirds of their species have died out, and altered patterns of infection because of changes in temperature seem to be the cause.

Losses in biodiversity and the emergence of new infectious diseases are among the greatest threats to life on the planet. The declines in amphibian populations lie at the interface between these issues.