- aut = "Aaron D. Kaplan"
- Artículo:
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
- Autor:
Xonia Carvajal-Vergara
Ana Sevilla
Sunita L. D’Souza
Yen-Sin Ang
Christoph Schaniel
Dung-Fang Lee
Lei Yang
Aaron D. Kaplan
Eric D. Adler
Roye Rozov
YongChao Ge
Ninette Cohen
Lisa J. Edelmann
Betty Chang
Avinash Waghray
Jie Su
Sherly Pardo
Klaske D. Lichtenbelt
Marco Tartaglia
Bruce D. Gelb
Ihor R. Lemischka
- Resumen:
The generation of induced pluripotent stem cells (iPSCs) from patients with defined genetic disorders promises to help the basic understanding of complex diseases and the development of therapeutics. Here iPSCs have been generated from patients with LEOPARD syndrome, a developmental disorder with pleiomorphic effects on several tissues and organs. The iPSCs are characterized and the phenotype of cardiomyocytes derived from these cells is investigated.
- Página:
808
- Publicación:
Nature
- Volúmen:
465
- Número:
7299
- Periodo:
10 Junio 2010
- ISSN:
00280836
- SrcID:
00280836-2010-06-10.txt
- Documento número 307783
- Actualizado el martes, 23 de mayo de 2017 03:58:18 p. m.
- Creado el martes, 23 de mayo de 2017 03:58:18 p. m.
- Enlace directo
- Artículo:
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
- Autor:
Xonia Carvajal-Vergara
Ana Sevilla
Sunita L. D’Souza
Yen-Sin Ang
Christoph Schaniel
Dung-Fang Lee
Lei Yang
Aaron D. Kaplan
Eric D. Adler
Roye Rozov
YongChao Ge
Ninette Cohen
Lisa J. Edelmann
Betty Chang
Avinash Waghray
Jie Su
Sherly Pardo
Klaske D. Lichtenbelt
Marco Tartaglia
Bruce D. Gelb
Ihor R. Lemischka
- Resumen:
The generation of induced pluripotent stem cells (iPSCs) from patients with defined genetic disorders promises to help the basic understanding of complex diseases and the development of therapeutics. Here iPSCs have been generated from patients with LEOPARD syndrome, a developmental disorder with pleiomorphic effects on several tissues and organs. The iPSCs are characterized and the phenotype of cardiomyocytes derived from these cells is investigated.
- Página:
808
- Publicación:
Nature
- Volúmen:
465
- Número:
7299
- Periodo:
10 Junio 2010
- ISSN:
00280836
- SrcID:
00280836-2010-06-10.txt
- Documento número 1206652
- Actualizado el martes, 10 de julio de 2018 11:33:59 a. m.
- Creado el martes, 10 de julio de 2018 11:33:59 a. m.
- Enlace directo
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