Many enzymes have a series of catalytic sites, lined up like beads on a string. A previously unknown link in one of these molecular assembly lines involves an unexpected approach to a common biochemical reaction.

Evolution has crafted thousands of enzymes that are efficient catalysts for a plethora of reactions. Human attempts at enzyme design trail far behind, but may benefit from exploiting evolutionary tactics.

However parkinsonism is initiated, the progressive symptoms are similarly devastating. So insights from analyses of gene mutations linked to these disorders should aid a better general understanding of them.