1. importsource = "00280836-2010-04-15.txt"
Se encontraron 141 resultados.
Artículo:

International network of cancer genome projects

Resumen:

The International Cancer Genome Consortium

Página:

993

Publicación:

Nature

Volúmen:

464

Número:

7291

Periodo:

15 Abril 2010

ISSN:

00280836

SrcID:

00280836-2010-04-15.txt

  • Documento número 307357
  • Actualizado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Creado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Enlace directo
Artículo:

Genome remodelling in a basal-like breast cancer metastasis and xenograft

Autor:

Li Ding

Resumen:

Massively parallel DNA sequencing allows entire genomes to be screened for genetic changes associated with tumour progression. Here, the genomes of four DNA samples from a 44-year-old African-American patient with basal-like breast cancer were analysed. The samples came from peripheral blood, the primary tumour, a brain metastasis and a xenograft derived from the primary tumour. The findings indicate that cells with a distinct subset of the primary tumour mutation might be selected during metastasis and xenografting

Página:

999

Publicación:

Nature

Volúmen:

464

Número:

7291

Periodo:

15 Abril 2010

ISSN:

00280836

SrcID:

00280836-2010-04-15.txt

  • Documento número 307358
  • Actualizado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Creado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Enlace directo
Artículo:

Molecular basis of infrared detection by snakes

Autor:

Elena O. Gracheva

Resumen:

Snakes are notoriously apt at generating 'thermal images' of predators or prey. The underlying physiology has been unclear, although in snakes such as pythons, vipers and boas, infrared signals are initially received by the pit organ. Here it is shown that pit-bearing snakes rely on heat detection by the ion channel TRPA1. This extends the sensory repertoire of the TRPA1 family of proteins, which detect chemical irritants in mammals and thermal variations in insects

Página:

1006

Publicación:

Nature

Volúmen:

464

Número:

7291

Periodo:

15 Abril 2010

ISSN:

00280836

SrcID:

00280836-2010-04-15.txt

  • Documento número 307359
  • Actualizado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Creado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Enlace directo
Artículo:

Real-time tRNA transit on single translating ribosomes at codon resolution

Autor:

Sotaro Uemura

Resumen:

Single-molecule studies allow biological processes to be examined one molecule at a time, as they occur. Here, zero-mode waveguides have been used to concentrate reactions in zeptolitre-sized volumes, making it possible to study real-time translocation by the ribosome. The binding of transfer RNAs (tRNAs) to the ribosome could be followed; the results show that tRNA release from the exit site is uncoupled from tRNA binding to the aminoacyl-tRNA site

Página:

1012

Publicación:

Nature

Volúmen:

464

Número:

7291

Periodo:

15 Abril 2010

ISSN:

00280836

SrcID:

00280836-2010-04-15.txt

  • Documento número 307360
  • Actualizado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Creado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Enlace directo
Artículo:

An image of an exoplanet separated by two diffraction beamwidths from a star

Autor:

E. Serabyn

Resumen:

Three exoplanets around the star HR 8799 have recently been discovered by differential imaging with large telescopes. In such cases, bright scattered starlight means that large angular offsets of the star are required for high-contrast imaging of the planets. Imaging at small angles requires a technique for reducing starlight and associated noise while still transmitting light from the planet. Here such a technique is described: all three HR 8799 planets have been detected using a vector vortex coronagraph on a small-aperture system

Página:

1018

Publicación:

Nature

Volúmen:

464

Número:

7291

Periodo:

15 Abril 2010

ISSN:

00280836

SrcID:

00280836-2010-04-15.txt

  • Documento número 307361
  • Actualizado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Creado el martes, 23 de mayo de 2017 03:58:15 p. m.
  • Enlace directo