- importsource = "00280836-2012-11-01.txt"
- Artículo:
An integrated map of genetic variation from 1,092 human genomesopen access
- Autor:
The 1000 Genomes Project Consortium
- Resumen:
This report from the 1000 Genomes Project describes the genomes of 1,092 individuals from 14 human populations, providing a resource for common and low-frequency variant analysis in individuals from diverse populations; hundreds of rare non-coding variants at conserved sites, such as motif-disrupting changes in transcription-factor-binding sites, can be found in each individual.
- Página:
56
- Sección:
ARTICLES
- Publicación:
Nature
- Volúmen:
491
- Número:
7422
- Fecha:
1 noviembre 2012
- ISSN:
00280836
- SrcID:
00280836-2012-11-01.txt
- Documento número 313348
- Actualizado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Creado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Enlace directo
- Artículo:
Generation of functional thyroid from embryonic stem cells
- Autor:
Francesco Antonica, Dominika Figini Kasprzyk, Robert Opitz, Michelina Iacovino, Xiao-Hui Liao+ et al.
- Resumen:
Transient overexpression of the transcription factors NKX2-1 and PAX8 in a murine cell model is shown to direct the differentiation of embryonic stem cells towards a thyroid follicular cell lineage; the resulting three-dimensional thyroid follicles created by subsequent thyrotropin treatment show hallmarks of thyroid function in vitro and rescue thyroid function in vivo when transplanted into athyroid mice, adding to our understanding of the molecular mechanisms underlying thyroid development.
- Página:
66
- Sección:
ARTICLES
- Publicación:
Nature
- Volúmen:
491
- Número:
7422
- Fecha:
1 noviembre 2012
- ISSN:
00280836
- SrcID:
00280836-2012-11-01.txt
- Documento número 313349
- Actualizado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Creado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Enlace directo
- Artículo:
Spontaneous network formation among cooperative RNA replicators
- Autor:
Nilesh Vaidya, Michael L. Manapat, Irene A. Chen, Ramon Xulvi-Brunet, Eric J. Hayden+ et al.
- Resumen:
In models of early life it has been suggested that life and evolution would be more easily achieved if RNA molecules could interact, rather than function independently; here an in vitro system is designed with several RNA fragments that can assemble into a ribozyme, showing that cooperative networks formed by these fragments outcompete self-catalytic RNA fragments.
- Página:
72
- Sección:
ARTICLES
- Publicación:
Nature
- Volúmen:
491
- Número:
7422
- Fecha:
1 noviembre 2012
- ISSN:
00280836
- SrcID:
00280836-2012-11-01.txt
- Documento número 313350
- Actualizado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Creado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Enlace directo
- Artículo:
Distinctive space weathering on Vesta from regolith mixing processes
- Autor:
C. M. Pieters, E. Ammannito, D. T. Blewett, B. W. Denevi, M. C. De Sanctis+ et al.
- Resumen:
Whereas space weathering of some airless bodies, such as the Moon, occurs through the accumulation on regolith of nanophase metallic particles, spectroscopic data show that space weathering of the asteroid Vesta occurs through the small-scale mixing of diverse surface components, which gradually generates locally homogenized upper regolith.
- Página:
79
- Sección:
LETTERS
- Publicación:
Nature
- Volúmen:
491
- Número:
7422
- Fecha:
1 noviembre 2012
- ISSN:
00280836
- SrcID:
00280836-2012-11-01.txt
- Documento número 313351
- Actualizado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Creado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Enlace directo
- Artículo:
Dark material on Vesta from the infall of carbonaceous volatile-rich material
- Autor:
T. B. McCord, J.-Y. Li, J.-P. Combe, H. Y. McSween, R. Jaumann+ et al.
- Resumen:
From spectra and images of Vesta, it is suggested that the dark patches on Vesta are formed of infalling hydrated carbonaceous material and the bright patches are uncontaminated Vesta soil.
- Página:
83
- Sección:
LETTERS
- Publicación:
Nature
- Volúmen:
491
- Número:
7422
- Fecha:
1 noviembre 2012
- ISSN:
00280836
- SrcID:
00280836-2012-11-01.txt
- Documento número 313352
- Actualizado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Creado el martes, 23 de mayo de 2017 03:58:52 p. m.
- Enlace directo