Origami, the ancient Japanese art of paper folding, is mathematically deeper than it looks. Delving into its complexities allows the construction of elaborate and useful structures from simple, flat templates.

In multiple sclerosis, the immune system attacks 'self' tissues. Ten years after the discovery of one target of this autoimmunity, work with mice identifies it as a guardian protein produced in response to inflammation.

Damaged or foreign DNA stimulates immune responses by inducing the production of interferon proteins. New evidence indicates that this response is mediated by a cytosolic DNA sensor known as DAI.