Número de Documento     
Artículo:

Biochemistry: Structural Bioinformatics-Based Design of Selective, Irreversible Kinase Inhibitors

Autor:

Michael S. Cohen et al

Resumen:

Analysis of the apparently similar catalytic sites of two ubiquitous enzymes enables the design of small molecules that inhibit only one of them, and therefore may be useful as targeted drugs.

Página:

1318

Sección:

Reports

Publicación:

Science

Volúmen:

308

Número:

5726

Fecha:

Mayo 27 2005

ISSN:

00368075

SrcID:

00368075-2005-05-27.txt

Número de Documento