Número de Documento     
Artículo:

Negative selection in humans and fruit flies involves synergistic epistasis

Autor:

MASHAAL SOHAIL

OLGA A. VAKHRUSHEVA

JAE HOON SUL

Resumen:

Ongoing selection against rare protein-disrupting mutations depends on an individual’s relative decline in fitness with each additional mutation.

Página:

539

Publicación:

Science

Volúmen:

356

Número:

6337

Periodo:

5 mayo 2017

ISSN:

00368075

SrcID:

00368075-2017-05-05.txt

Número de Documento